active

Thiamine Hcl(Vitamin B1 Derivatives)

INCI: THIAMINE HCL
CAS 67-03-8
Antioxidant support; skin energy co-factor; skin conditioning
Limited Data
Insufficient safety data available. Consider enriching this ingredient.
Details

Description

Antioxidant support; skin energy co-factor; skin conditioning

Purpose

Function

Antioxidant support; skin energy co-factor; skin conditioning
Profile

Properties

Silicone
Silicone free
Compliance

Regulatory Status

EU
Permitted
Safety
GOOD
US
Permitted
Absorptionlow
Sensitizationnone
MoSadequate
NOAEL1000 mg/kg
ConcernLow
Flags
antioxidant-supportminimal-cosmetic-datano-cir-assessmentenergy-co-factorwater-solublesafe-by-analogyfda_food_additive
Verdict

Minimal cosmetic relevance compared to niacinamide and panthenol — included in vitamin B complex formulations primarily for completeness or synergy claims. Safe by analogy with extensive oral vitamin safety, best positioned as a minor antioxidant support ingredient in multi-vitamin or skin-energy concept formulations.

US Note

No CIR-specific safety assessment for standalone cosmetic use. Thiamine HCl is an essential vitamin with well-established oral safety. FDA-GRAS for food use. Minimal dedicated topical cosmetic research. EU imposes no specific restrictions. Use based on general vitamin safety profile.

Assessment

Ratings

Comedogenic0/5
LowHigh
Irritancy0/5
LowHigh
Reference

Identifiers

CAS Number
67-03-8
INCI
THIAMINE HCL
Category
active
Updated
Apr 2, 2026