active

Panax Ginseng (Asian Ginseng) Root Extract

INCI: PANAX GINSENG ROOT EXTRACT
CAS 84650-12-4
Extract from Panax ginseng roots. Active constituents: ginsenosides (steroidal saponins with antioxidant, anti-inflammatory, and collagen-stimulating activity), polysaccharides (hydration), and polyacetylenes. Mechanisms: ginsenosides inhibit MMP-1 (collagen-degrading enzyme) and stimulate procollagen synthesis in fibroblasts; antioxidant via free-radical scavenging; brightening via inhibition of melanin synthesis.
Limited Data
Insufficient safety data available. Consider enriching this ingredient.
Details

Description

Extract from Panax ginseng roots. Active constituents: ginsenosides (steroidal saponins with antioxidant, anti-inflammatory, and collagen-stimulating activity), polysaccharides (hydration), and polyacetylenes. Mechanisms: ginsenosides inhibit MMP-1 (collagen-degrading enzyme) and stimulate procollagen synthesis in fibroblasts; antioxidant via free-radical scavenging; brightening via inhibition of melanin synthesis.

Purpose

Function

Extract from Panax ginseng roots. Active constituents: ginsenosides (steroidal saponins with antioxidant, anti-inflammatory, and collagen-stimulating activity), polysaccharides (hydration), and polyacetylenes. Mechanisms: ginsenosides inhibit MMP-1 (collagen-degrading enzyme) and stimulate procollagen synthesis in fibroblasts; antioxidant via free-radical scavenging; brightening via inhibition of melanin synthesis.
Profile

Properties

Silicone
Silicone free
Compliance

Regulatory Status

EU
Permitted
Safety
GOOD
US
Permitted
Absorptionmoderate
Sensitizationlow
MoSnot established
ConcernLow
Flags
adaptogenantioxidantanti-agingcollagen-synthesisk-beautyholistic-beautymmp-inhibitor
Verdict

Ginseng extract offers strong in-vitro evidence for cosmetic use with documented MMP-1 inhibition and procollagen synthesis stimulation via ginsenosides. Clinical performance is well-established in K-beauty contexts, though robust independent RCTs for topical use remain limited. Fermented ginseng shows enhanced bioavailability. Antioxidant and collagen-support claims can be substantiated from available in-vitro data.

US Note

Permitted without restriction. Strong market presence in K-beauty and premium anti-aging segments. Topical ginsenoside efficacy supported by in-vitro and some clinical data. MoCRA safety substantiation required.

Assessment

Ratings

Comedogenic0/5
LowHigh
Irritancy0/5
LowHigh
Reference

Identifiers

CAS Number
84650-12-4
INCI
PANAX GINSENG ROOT EXTRACT
Category
active
Updated
Apr 2, 2026