active

Palmitoyl Tetrapeptide-7

INCI: PALMITOYL TETRAPEPTIDE-7
CAS 221227-05-0
Palmitoyl Tetrapeptide-7 is the reaction product of palmitic acid and Tetrapeptide-7
Limited Data
Insufficient safety data available. Consider enriching this ingredient.
Details

Description

Palmitoyl Tetrapeptide-7 is the reaction product of palmitic acid and Tetrapeptide-7

Purpose

Function

Skin-conditioning agent; anti-inflammatory peptide
Profile

Properties

Silicone
Silicone free
Compliance

Regulatory Status

EU
Permitted
Safety
GOOD
US
Permitted
Absorptionhigh
Sensitizationlow
MoSadequate
ConcernLow
Flags
peptidematrikinecollagen-stimulatinganti-inflammatoryanti-agingeye-areamatrixyleyeliss
Verdict

Palmitoyl Tetrapeptide-7 is confirmed safe as used in cosmetics by CIR Expert Panel. The peptide decreases IL-6 secretion after UVB exposure and stimulates collagen synthesis; in clinical studies it demonstrated significant reductions in wrinkle depth, volume, and number with no regulatory restrictions.

US Note

Explicitly named in CIR safety assessment as safe as used in cosmetics. Covered under same CIR review as Tripeptide-1 and Hexapeptide-12 derivatives.

Assessment

Ratings

Comedogenic0/5
LowHigh
Irritancy0/5
LowHigh
Reference

Identifiers

CAS Number
221227-05-0
INCI
PALMITOYL TETRAPEPTIDE-7
Category
active
Updated
Apr 2, 2026