Hypericum Perforatum Extract
Description
Hypericum Perforatum Extract is an extract of the capsules, flowers, leaves and stem heads of the St. John's wort, Hypericum perforatum L., Hypericaceae
Function
Properties
Regulatory Status
Hypericum Perforatum Extract contains hypericin and hyperforin responsible for antimicrobial and anti-inflammatory properties in wound-healing applications. EU: Hypericin is restricted under Annex III due to phototoxicity potential with concentration limits on hypericin content that must be addressed in CPSR. Formulations should be used as PM applications or with SPF ≥30 protection to mitigate phototoxicity risk. US: Permitted as cosmetic ingredient with no specific concentration restrictions, though phototoxicity is documented. Wound healing claims trigger drug classification in both EU and US.
Permitted as cosmetic ingredient. No specific FDA concentration restrictions. Phototoxicity risk from hypericin content should be addressed in CPSR/safety substantiation. Wound healing claims trigger drug classification.