Humectant

Hyaluronic Acid

Also known as HA
INCI: HYALURONIC ACID
CAS 9004-61-9 EC 232-678-0
It’s the - sodium form - cousin of the famous NMF, hyaluronic acid (HA). If HA does not tell you anything we have a super detailed, geeky...
Generally Safe
This ingredient has a good safety profile based on available data.
Details

Description

It’s the - sodium form - cousin of the famous NMF, hyaluronic acid (HA). If HA does not tell you anything we have a super detailed, geeky...

Purpose

Function

Skin conditioning agent, humectantMoisturizingAnti-aging
Profile

Properties

Vegan
Yes
Silicone
Silicone free
Origin
Synthetic
Compliance

Regulatory Status

EU
Permitted
Safety
EXCELLENT
US
Permitted
Absorptionlow
Sensitizationnone
MoSadequate
NOAEL1333 mg/kg
ConcernLow
Verdict

Animal-sourced HA (rooster comb) must be free of pathogenic viruses, infectious agents, and biologically-derived impurities. Bacterial fermentation-derived HA is nearly endotoxin-free. No genotoxicity, no reproductive toxicity, acute oral LD50 >1200 mg/kg in mice.

US Note

Permitted — no CFR restriction; also used as inactive ingredient in FDA-approved drugs at up to 0.01% topical

Assessment

Ratings

Comedogenic0/5
LowHigh
Irritancy0/5
LowHigh
Reference

Identifiers

CAS Number
9004-61-9
EC Number
232-678-0
INCI
HYALURONIC ACID
Category
Humectant
Updated
Apr 2, 2026