active

Gluconic Acid

INCI: GLUCONIC ACID
CAS 526-95-4 EC 208-401-4
D-gluconic acid
Limited Data
Insufficient safety data available. Consider enriching this ingredient.
Details

Description

D-gluconic acid

Purpose

Function

Exfoliant
Profile

Properties

Silicone
Silicone free
Compliance

Regulatory Status

EU
Permitted
Safety
GOOD
US
Permitted
EU Max Concentration50%
Absorptionmoderate
Sensitizationlow
MoSnot established
NOAEL4100 mg/kg
ConcernLow
Flags
epa_safer_alternativefda_food_additive
Verdict

Good safety profile with established use as an exfoliant; generally considered safe for cosmetic applications.

US Note

CIR: S - IJT 38(S1):5-38, 2019

Assessment

Ratings

Comedogenic0/5
LowHigh
Irritancy0/5
LowHigh
Reference

Identifiers

CAS Number
526-95-4
EC Number
208-401-4
INCI
GLUCONIC ACID
Category
active
Updated
Apr 2, 2026