active

Fullerenes

INCI: FULLERENES
CAS 115383-22-7
Fullerenes is a class of carbon molecules characterized by an icosohedron structure
Limited Data
Insufficient safety data available. Consider enriching this ingredient.
Details

Description

Fullerenes is a class of carbon molecules characterized by an icosohedron structure

Purpose

Function

Antioxidant
Profile

Properties

Silicone
Silicone free
Compliance

Regulatory Status

EU
Permitted
Safety
POOR
US
Permitted
Absorptionhigh
Sensitizationhigh
MoSnot established
ConcernHigh
Flags
nano-formcarcinogen-concernsccs-opinioneu-regulatory-riskgenotoxicity-concern
Verdict

Fullerenes (C60, C70) are permitted under EU law but safety cannot be established due to unresolved genotoxicity concerns, lack of toxicokinetic data, and insufficient dermal absorption characterization per SCCS Final Opinion SCCS/1649/23; hydroxylated fullerenes were assessed as genotoxic and not safe.

US Note

No FDA GRAS classification or specific cosmetic restriction identified. FDA issued a warning letter to Bioactive C60/FullerlifeC60 LLC (605954, dated 30 March 2020) concerning unapproved drug claims for C60 fullerene products. No formal CIR cosmetic ingredient safety assessment exists. Not classified as a sunscreen active under FDA OTC monograph rules.

Assessment

Ratings

Comedogenic0/5
LowHigh
Irritancy0/5
LowHigh
Reference

Identifiers

CAS Number
115383-22-7
INCI
FULLERENES
Category
active
Updated
Apr 2, 2026