Curcuma Longa Extract

Curcuma longa extract (curcumin, demethoxycurcumin, bisdemethoxycurcumin) is permitted in EU cosmetics under Regulation (EC) No 1223/2009 without specific Annex restrictions. Not listed in Annex II or Annex III. No dedicated SCCS opinion. CIR has not issued a final safety assessment for curcumin as a cosmetic ingredient. In the US, no FDA pre-market approval is required for cosmetic use; curcumin (CI 75300) is an approved color additive for food use. Bioavailability is the central limitation due to poor aqueous solubility and rapid metabolism. In vitro antioxidant potency confirmed. Heavy metal and mycotoxin contamination risk from raw Ayurvedic supply chains requires supplier COA and DNA barcoding authentication.

No FDA pre-market approval required for cosmetic use. Curcumin (CI 75300) is an FDA-approved color additive for food (21 CFR 73.600). Not approved as OTC drug active. No CIR final safety assessment for cosmetic use. MoCRA safety substantiation required. No GRAS listing relevant to topical use.