Active Compound

Copper Peptides GHK-Cu

Skin conditioning, wound healing
Limited Data
Insufficient safety data available. Consider enriching this ingredient.
Details

Description

Skin conditioning, wound healing

Purpose

Function

Skin conditioning, wound healing
Profile

Properties

Silicone
Silicone free
Compliance

Regulatory Status

EU
Permitted
Safety
GOOD
US
Permitted
Absorptionlow
Sensitizationlow
MoSadequate
NOAEL1600 mg/kg
ConcernLow
Verdict

EU: Not listed in Annex II or III of EC 1223/2009; permitted as skin conditioning agent. Copper nano form separately regulated under EU 2024/858. US: Permitted per FDA VCRP; CIR Expert Panel concluded safe in cosmetics at present concentrations (2018). FDA-cleared wound care product confirms biocompatibility.

US Note

Permitted cosmetic ingredient registered in FDA VCRP. CIR Expert Panel safety conclusion published 2018 covers Copper Tripeptide-1 and related metal salt peptides. Not an FDA-approved OTC drug ingredient. Iamin hydrating gel is FDA-cleared wound-care product containing the ingredient. No FDA restrictions on cosmetic use at standard concentrations (less than 10 ppm).

Assessment

Ratings

Comedogenic0/5
LowHigh
Irritancy0/5
LowHigh
Reference

Identifiers

Category
Active Compound
Updated
Apr 23, 2026

No registry identifiers available for this ingredient.