Plant Extracts

Citrus Paradisi (Grapefruit) Peel Extract

INCI: CITRUS PARADISI PEEL EXTRACT
CAS 8016-20-4
essential oil
Limited Data
Insufficient safety data available. Consider enriching this ingredient.
Details

Description

essential oil

Purpose

Function

Skin conditioning; Antioxidant; Fragrance. Extract obtained from the peel of grapefruit, Citrus paradisi (syn. Citrus grandis). Contains flavonoids (naringin, naringenin), limonene, and furanocoumarins. Provides antioxidant protection and skin conditioning. Reported among the highest-use citrus peel-derived ingredients with 61 total reported uses, more than half in skin care preparations. CIR Expert Panel assessed 47 citrus peel-derived ingredients; concluded they are safe for use in both rinse-off and leave-on cosmetic products when formulated to be non-sensitizing and non-irritating, with leave-on products not exceeding 0.0015% (15 ppm) 5-MOP.
Profile

Properties

Silicone
Silicone free
Compliance

Regulatory Status

EU
Permitted
Safety
GOOD
US
Permitted
EU Max ConcentrationLeave-on products: 15 ppm (0.0015%) 5-methoxypsoralen (5-MOP)
Absorptionlow
Sensitizationlow
MoSadequate
ConcernLow
Flags
plant-extractantioxidantskin-conditioningfurocoumarinphototoxicity-riskcir-reviewedbotanicalgrapefruitflavonoidsifra_fragrancefda_food_additive
Verdict

CIR-affirmed safe for rinse-off and leave-on use when formulated below furocoumarin thresholds. Well-tolerated skin conditioning and antioxidant ingredient with good safety profile; primary concern is furocoumarin-mediated phototoxicity in leave-on products, requiring 5-MOP not to exceed 15 ppm in finished formulation.

US Note

Not specifically restricted by FDA for cosmetic use. Widely used in cosmetics under standard safety substantiation requirements. Formulators should monitor furocoumarin content and restrict leave-on concentrations accordingly.

Assessment

Ratings

Comedogenic0/5
LowHigh
Irritancy0/5
LowHigh
Reference

Identifiers

CAS Number
8016-20-4
INCI
CITRUS PARADISI PEEL EXTRACT
Category
Plant Extracts
Updated
Apr 23, 2026