Botanical Extract

Citrus Grandis Seed Extract (Grapefruit).

Skin conditioning; antimicrobial; antioxidant. Extract obtained from the seeds of the grapefruit, Citrus grandis (syn. Citrus paradisi). Contains flavonoids (naringenin, hesperidin), limonoids, and vitamin C precursors. Used in cosmetics as a skin conditioning and antioxidant active, with natural preservation-enhancing properties. Reported in 144 cosmetic product uses, with a majority in leave-on skin care preparations.
Limited Data
Insufficient safety data available. Consider enriching this ingredient.
Details

Description

Skin conditioning; antimicrobial; antioxidant. Extract obtained from the seeds of the grapefruit, Citrus grandis (syn. Citrus paradisi). Contains flavonoids (naringenin, hesperidin), limonoids, and vitamin C precursors. Used in cosmetics as a skin conditioning and antioxidant active, with natural preservation-enhancing properties. Reported in 144 cosmetic product uses, with a majority in leave-on skin care preparations.

Purpose

Function

Skin conditioning; antimicrobial; antioxidant. Extract obtained from the seeds of the grapefruit, Citrus grandis (syn. Citrus paradisi). Contains flavonoids (naringenin, hesperidin), limonoids, and vitamin C precursors. Used in cosmetics as a skin conditioning and antioxidant active, with natural preservation-enhancing properties. Reported in 144 cosmetic product uses, with a majority in leave-on skin care preparations.
Profile

Properties

Silicone
Silicone free
Compliance

Regulatory Status

EU
Permitted
Safety
GOOD
US
Permitted
Absorptionlow
Sensitizationlow
MoSnot established
NOAEL5 mg/kg
ConcernLow
Flags
plant-extractantioxidantskin-conditioningantimicrobialcir-reviewedbotanicalflavonoidsgrapefruitfda_food_additive
Verdict

Well-established cosmetic ingredient with CIR-affirmed safety at typical use concentrations, valued for skin conditioning and antioxidant activity with a broad safety profile. No EU restrictions apply; not FDA-regulated as an active. cGMP controls recommended to minimize botanical impurities.

US Note

Not specifically regulated by FDA for cosmetic use. Commercially marketed as a natural preservative booster; FDA has not issued any restriction. Formulators should ensure finished products comply with 21 CFR labeling and safety requirements.

Assessment

Ratings

Comedogenic0/5
LowHigh
Irritancy0/5
LowHigh
Reference

Identifiers

Category
Botanical Extract
Updated
Apr 2, 2026

No registry identifiers available for this ingredient.