Skin Conditioning

Bis(Tripeptide-1) Copper Acetate

CAS 130120-57-9
Cuprate (1-), (glycyl-L-histidyl-N1-L-lysinato)[glycyl-N-L-histidyl-N,N3-L-lysinato(2-)]-, hydrogen, diacetate
Limited Data
Insufficient safety data available. Consider enriching this ingredient.
Details

Description

Cuprate (1-), (glycyl-L-histidyl-N1-L-lysinato)[glycyl-N-L-histidyl-N,N3-L-lysinato(2-)]-, hydrogen, diacetate

Purpose

Function

Skin conditioning; promotes collagen synthesis, wound healing, and hair growth stimulation
Profile

Properties

Silicone
Silicone free
Compliance

Regulatory Status

EU
Permitted
Safety
MODERATE
US
Permitted
Absorptionlow
Sensitizationlow
MoSnot established
ConcernModerate
Verdict

Generally considered safe at typical use levels. Contains copper ions - excessive concentrations could theoretically cause irritation, but formulation levels are very low (usually ppm range). A copper-complexed dimer of Tripeptide-1 (GHK peptide - Glycyl-L-Histidyl-L-Lysine) with acetate counter-ion. Appears as a clear bluish liquid due to copper ions. Originally isolated from human plasma; stimulates dermal cell proliferation, enhances skin elasticity, reduces fine lines, and strengthens hai...

US Note

Allowed - no specific prohibition; subject to general safety requirements. EWG hazard score: 1 (low concern)

Assessment

Ratings

Comedogenic0/5
LowHigh
Irritancy0/5
LowHigh
Reference

Identifiers

CAS Number
130120-57-9
Category
Skin Conditioning
Updated
Apr 23, 2026