Cosmetic Ingredient

Benzophenone-1

INCI: BENZOPHENONE-1
CAS 131-56-6 [^1_7] EC 205-029-4
2,4-Dihydroxybenzophenone
Limited Data
Insufficient safety data available. Consider enriching this ingredient.
Details

Description

2,4-Dihydroxybenzophenone

Purpose

Function

UV absorber, light stabilizer (protects formulations from UV degradation)
Profile

Properties

Silicone
Silicone free
Compliance

Regulatory Status

EU
Banned
Safety
POOR
US
Permitted
Absorptionmoderate
Sensitizationmoderate
MoSadequate
NOAEL50 mg/kg
ConcernHigh
Verdict

SCCS considers benzophenone-1 not safe due to unresolved genotoxicity and endocrine disrupting properties; exhibits strong estrogen receptor activity; detected in human urine and blood as metabolite of benzophenone-3; EU prohibition or severe restriction expected following SCCS opinion; cross-contamination risk from benzophenone-3 metabolism.

US Note

Not an approved OTC sunscreen active; permitted as cosmetic ingredient (non-sunscreen function); no FDA restriction currently

Assessment

Ratings

Comedogenic0/5
LowHigh
Irritancy0/5
LowHigh
Reference

Identifiers

CAS Number
131-56-6 [^1_7]
EC Number
205-029-4
INCI
BENZOPHENONE-1
Category
Cosmetic Ingredient
Updated
Apr 2, 2026