Bakuchíol
Description
Retinol functional analog (non-retinoid); promotes epidermal keratinocyte turnover and melanin dispersal; modest tyrosinase inhibitor; antioxidant; anti-inflammatory; acts on retinoid receptors without being a retinoid molecule
Function
Properties
Regulatory Status
Plant-derived retinoid alternative from Psoralea corylifolia with dual value in brightening formulations through modest direct tyrosinase inhibition and retinol-like keratinocyte turnover promotion. A 2024 systematic review of 15 clinical trials confirmed efficacy for post-inflammatory hyperpigmentation, aging, and acne with good tolerability. Bakuchiol functions best as a complementary ingredient alongside primary tyrosinase inhibitors rather than as a standalone brightening active. Key advantages versus retinoids include no photosensitization, pregnancy compatibility, and exemption from EU 2024/996 Vitamin A concentration restrictions, making it excellent for sensitive skin and darker phototypes.
No FDA restrictions. Not a retinoid and not subject to OTC drug classification for retinoids. No concentration restrictions. Safety supported by botanical extract precedent and growing clinical trial database.
Ratings
Identifiers
No registry identifiers available for this ingredient.