Plant Extracts

Azadirachta Indica (Neem) Leaf Extract

INCI: AZADIRACHTA INDICA LEAF EXTRACT
CAS 84696-25-3
Skin Conditioning
Limited Data
Insufficient safety data available. Consider enriching this ingredient.
Details

Description

Skin Conditioning

Purpose

Function

Skin Conditioning
Profile

Properties

Silicone
Silicone free
Compliance

Regulatory Status

EU
Permitted
Safety
GOOD
US
Permitted
Absorptionmoderate
Sensitizationlow
MoSnot established
ConcernLow
Flags
enhanced-skin-absorptionendocrine-disruption-lowecotoxicology-lowewg-verified-restrictedno-cir-assessmentpatch-test-recommendedseed-extract-eu-banned-leaf-not
Verdict

Safe for cosmetic use. Leaf extract is distinct from the prohibited kernel (seed) extract and carries no EU or US restriction. Well-documented antimicrobial, antifungal, anti-inflammatory, and antioxidant profile supports use in acne, skin conditioning, and problem-skin formulations.

US Note

No GRAS designation required for topical cosmetic use. FDA has not flagged this ingredient. EWG VERIFIED status requires adequate substantiation due to enhanced absorption concern.

Assessment

Ratings

Comedogenic1/5
LowHigh
Irritancy1/5
LowHigh
Reference

Identifiers

CAS Number
84696-25-3
INCI
AZADIRACHTA INDICA LEAF EXTRACT
Category
Plant Extracts
Updated
Apr 2, 2026