Avobenzone
INCI: AVOBENZONE
CAS 70356-09-1
Broad-spectrum UVA filter (340-400nm)
Limited Data
Insufficient safety data available. Consider enriching this ingredient.
Details
Description
Broad-spectrum UVA filter (340-400nm)
Purpose
Function
Broad-spectrum UVA filter (340-400nm)
Profile
Properties
Silicone
Silicone free
Compliance
Regulatory Status
EU
Permitted
Safety
GOOD
US
Restricted
EU Max Concentration5%
Absorptionhigh
Sensitizationlow
MoSadequate
NOAEL450 mg/kg
ConcernModerate
Flags
systemic-absorptionfda-not-grasephotostability-concernphotoallergy-riskuva-filterannex-viifra_fragranceeu_cosing_listed
Verdict
Broad-spectrum UVA filter (340-400nm) permitted in EU at max 5% (Annex VI Entry 8). US FDA max 3%, classified not GRAS pending additional systemic toxicology data but not considered unsafe. MoS >100. No genotoxicity or endocrine disruption concerns.
US Note
FDA OTC monograph active ingredient. Max concentration 3% in US. Classified not GRAS per September 27, 2021 proposed administrative order (86 FR 53546) due to systemic absorption exceeding 0.5 ng/mL threshold. FDA stated this does NOT mean the ingredient is unsafe — products remain on market and recommended for continued use. Additional nonclinical toxicology data (carcinogenicity, reproductive) required by FDA.
Assessment
Ratings
Reference