Active Compound

Asiaticoside (8

anti-inflammatory, wound-healing, barrier-repair
Limited Data
Insufficient safety data available. Consider enriching this ingredient.
Details

Description

anti-inflammatory, wound-healing, barrier-repair

Purpose

Function

anti-inflammatory, wound-healing, barrier-repair
Profile

Properties

Silicone
Silicone free
Compliance

Regulatory Status

EU
Permitted
Safety
EXCELLENT
US
Permitted
Absorptionhigh
Sensitizationnone
MoSnot established
NOAEL1000 mg/kg
ConcernNone
Flags
activewound-healinganti-inflammatorybarrier-repaircollagen-stimulatorfilaggrin-boosterinvolucrin-boosternf-kb-inhibitorcentella-asiaticabotanicalatopic-dermatitis-targetsensitive-skin
Verdict

Excellent wound-healing and barrier-repair active from Centella asiatica that stimulates type I collagen synthesis, promotes fibroblast proliferation, upregulates filaggrin and involucrin expression, and inhibits NF-κB-mediated inflammatory pathways. Frequently formulated with madecassoside for synergistic barrier repair and anti-inflammatory benefit.

US Note

Permitted; no US concentration cap. Co-active with madecassoside in Centella asiatica triterpene extract. Used at 0.1–1% in leave-on formulations.

Assessment

Ratings

Comedogenic0/5
LowHigh
Irritancy0/5
LowHigh
Reference

Identifiers

Category
Active Compound
Updated
Apr 2, 2026

No registry identifiers available for this ingredient.