Ascorbyl Tetraisopalmitate
INCI: ASCORBYL TETRAISOPALMITATE
CAS 183476-82-6
L-ascorbic acid, tetraisohexadecanoate
Limited Data
Insufficient safety data available. Consider enriching this ingredient.
Details
Description
L-ascorbic acid, tetraisohexadecanoate
Purpose
Function
Oil-soluble vitamin C derivative; tyrosinase inhibitor; antioxidant; requires esterase-mediated hydrolysis to release ascorbic acid in skin; brightening active in anhydrous and oil-dominant formulations
Profile
Properties
Silicone
Silicone free
Compliance
Regulatory Status
EU
Permitted
Safety
EXCELLENT
US
Permitted
Absorptionhigh
Sensitizationmoderate
MoSadequate
ConcernModerate
Flags
cir-safe-as-used-2022eu-unrestrictedoil-solublesuperior-stabilitylipophilickorea-functional-cosmetic-whitening
Verdict
CIR safe as used (2022 update). Oil-soluble vitamin C derivative with superior stability shielded from oxidation. Lipophilic with limited systemic exposure. EU unrestricted and Korea MFDS approved functional cosmetic whitening active. Primary concern is allergic contact dermatitis cases; not recommended as primary brightening choice where alternatives with better safety records exist.
US Note
No FDA restriction. Allergic contact dermatitis cases published; use with caution. Not recommended as primary brightening active where alternatives with better safety records exist.
Assessment
Ratings
Reference