antioxidant

Ascorbyl Palmitate(C-Ester)

Also known as AscorbylPalmitate
INCI: ASCORBYL PALMITATE
CAS 137-66-6
Lipophilic antioxidant; ester of ascorbic acid and palmitic acid; product stabiliser; skin-conditioning agent; converted to ascorbic acid after ester cleavage by skin esterases
Limited Data
Insufficient safety data available. Consider enriching this ingredient.
Details

Description

Lipophilic antioxidant; ester of ascorbic acid and palmitic acid; product stabiliser; skin-conditioning agent; converted to ascorbic acid after ester cleavage by skin esterases

Purpose

Function

Lipophilic antioxidant; ester of ascorbic acid and palmitic acid; product stabiliser; skin-conditioning agent; converted to ascorbic acid after ester cleavage by skin esterases
Profile

Properties

Silicone
Silicone free
Compliance

Regulatory Status

EU
Permitted
Safety
EXCELLENT
US
Permitted
EU Max Concentration1%
Absorptionhigh
Sensitizationlow
MoSadequate
NOAEL1000 mg/kg
ConcernNone
Flags
antioxidantlipophilicvitamin-c-derivativeoil-phase-compatiblestable-esterproduct-stabilisersynergistic-with-vitamin-egrascir-reviewedeu_children_restrictedepa_safer_alternativeifra_fragrancefda_food_additive
Verdict

Lipophilic vitamin C derivative offering oil-phase compatibility and stability at neutral pH, essential for emulsions and lipid-based formulations where L-ascorbic acid is impractical. Functions as both a skin active after ester cleavage and a product antioxidant. Best use: product stabilisation in lipid phases (0.01–0.1%) or as skin active in oil-serum or lipid-based formulations (0.1–0.5%). Synergistic with alpha-tocopherol in vitamin E regeneration network. No regulatory restrictions.

US Note

FDA GRAS for food use as antioxidant preservative. No specific cosmetic concentration limits. Widely used in lipid-based formulations and oil-phase stabilisation. CIR assessed safe as used.

Assessment

Ratings

Comedogenic0/5
LowHigh
Irritancy0/5
LowHigh
Reference

Identifiers

CAS Number
137-66-6
INCI
ASCORBYL PALMITATE
Category
antioxidant
Updated
Apr 2, 2026