Cosmetic Ingredient

Ascorbyl Isostearate

INCI: ASCORBYL ISOSTEARATE
CAS 51222-59-4
Ascorbyl Isostearate is the ester of Ascorbic Acid and isostearic acid
Limited Data
Insufficient safety data available. Consider enriching this ingredient.
Details

Description

Ascorbyl Isostearate is the ester of Ascorbic Acid and isostearic acid

Purpose

Function

Skin-Conditioning Agent – Miscellaneous
Profile

Properties

Silicone
Silicone free
Compliance

Regulatory Status

EU
Permitted
Safety
MODERATE
US
Permitted
Absorptionlow
Sensitizationlow
MoSnot established
ConcernModerate
Verdict

Zero reported commercial uses as of 2022 CIR survey. If planning to use this ingredient, safety case would need to be established from scratch with read-across justification.

US Note

CIR-reviewed (2022): safe as used when formulated to be nonirritating/nonsensitizing; however, not reported as being used in any cosmetic products at the time of the review

Assessment

Ratings

Comedogenic0/5
LowHigh
Irritancy0/5
LowHigh
Reference

Identifiers

CAS Number
51222-59-4
INCI
ASCORBYL ISOSTEARATE
Category
Cosmetic Ingredient
Updated
Apr 2, 2026