Asarum Sieboldi Root Extract

Critical — Asarum species may contain aristolochic acids, which are classified as known human carcinogens (Group 1 by IARC) with nephrotoxic effects. Aristolochic acid content varies by species and plant part; rhizome/root preparations require batch testing. FDA banned aristolochic acid-containing botanicals from dietary supplements and urged cosmetic manufacturers to verify absence.

Not specifically restricted by FDA for cosmetic use; however, FDA has issued warnings (2000–2001) urging manufacturers to ensure botanical products are free of aristolochic acids