Humectant

Anhydroxylitol

INCI: ANHYDROXYLITOL
CAS 53448-53-6 EC 258-560-9
D-Xylitol, 1,4-Anhydro-
Limited Data
Insufficient safety data available. Consider enriching this ingredient.
Details

Description

D-Xylitol, 1,4-Anhydro-

Purpose

Function

Skin Conditioning Agent – Humectant
Profile

Properties

Silicone
Silicone free
Compliance

Regulatory Status

EU
Permitted
Safety
GOOD
US
Permitted
Absorptionlow
Sensitizationlow
MoSadequate
ConcernLow
Verdict

Safe for cosmetic use; CIR determined no identified risk substances in composition and myocarditis findings in rat studies were species-specific background findings with no relevance to human risk.

US Note

CIR Final Report (September 2021): Safe; 153 reported uses in VCRP — the most widely used ingredient in this saccharide group

Assessment

Ratings

Comedogenic0/5
LowHigh
Irritancy0/5
LowHigh
Reference

Identifiers

CAS Number
53448-53-6
EC Number
258-560-9
INCI
ANHYDROXYLITOL
Category
Humectant
Updated
Apr 2, 2026