conditioning-agent

Amodimethicone

INCI: AMODIMETHICONE
CAS 68554-54-1
Dimethylsiloxane, polymer, (((3-((2-aminoethyl)amino)propyl)-dimethoxysilyl)oxy)-terminated
Limited Data
Insufficient safety data available. Consider enriching this ingredient.
Details

Description

Dimethylsiloxane, polymer, (((3-((2-aminoethyl)amino)propyl)-dimethoxysilyl)oxy)-terminated

Purpose

Function

hair conditioning, film-forming, anti-static, cuticle repair
Profile

Properties

Silicone
Silicone free
Compliance

Regulatory Status

EU
Permitted
Safety
GOOD
US
Permitted
Absorptionnegligible
Sensitizationlow
MoSadequate
NOAEL1000 mg/kg
ConcernLow
Flags
cir-approvednon-volatile-siliconeamino-siliconeheat-protectionhair-buildup-risktargeted-cuticle-repaircosmos-prohibitedeu_children_restricted
Verdict

Amino-functional silicone that preferentially deposits on damaged cuticle sites due to cationic amino functionality attracting to anionic sites on damaged keratin. Reduces inter-fiber friction 40-60% and wet combing force. Provides heat protection above 200°C for thermal styling products. Not subject to EU cyclic siloxane restrictions. Regular use may cause buildup requiring clarifying shampoo. CIR and SCCS raise no major safety concerns. Superior targeted conditioning versus non-functional dimethicone in rinse-off hair care.

US Note

CIR assessed safe for topical use; large molecular weight prevents significant skin absorption; no FDA restriction

Assessment

Ratings

Comedogenic0/5
LowHigh
Irritancy0/5
LowHigh
Reference

Identifiers

CAS Number
68554-54-1
INCI
AMODIMETHICONE
Category
conditioning-agent
Updated
Apr 2, 2026