Ammonium Glycrrhizate

Well-characterized, CIR-cleared ingredient with strong anti-inflammatory and soothing efficacy profile. CIR supports up to 5% use concentration with good safety margin given negligible dermal absorption. Eye irritation CLP classification is a manufacturing/occupational hazard designation, not a cosmetic restriction. Use CIR 2007 final report as primary safety dossier reference. COSMOS/ECOCERT eligible if plant-derived from Glycyrrhiza glabra. Suitable for aqueous phase incorporation.

CIR 2007 concluded safe as used; licorice derivatives hold GRAS status as direct food ingredients with oral glycyrrhizic acid limits; European SCF recommended ≤100 mg/day oral intake (food context only, not relevant to cosmetics given negligible dermal absorption); no FDA cosmetic restrictions