Aminobutyric Acid
INCI: AMINOBUTYRIC ACID
CAS 56-12-2 EC 200-258-6
4-Aminobutyric acid
Limited Data
Insufficient safety data available. Consider enriching this ingredient.
Details
Description
4-Aminobutyric acid
Purpose
Function
Skin conditioning agent, anti-aging active
Profile
Properties
Silicone
Silicone free
Compliance
Regulatory Status
EU
Permitted
Safety
GOOD
US
Permitted
Absorptionlow
Sensitizationlow
MoSnot established
ConcernLow
Flags
anti-agingbotox-likemuscle-relaxingskin-conditioningdata-gapsno-cir-reportfda_food_additive
Verdict
Promising anti-aging efficacy with MMP-1 inhibition, procollagen synthesis promotion, filaggrin upregulation, and AQP3 enhancement; incomplete toxicological profile lacking CIR report, SCCS opinion, dermal absorption study, and established margin of safety.
US Note
No CIR report exists for GABA/Aminobutyric Acid; no OTC drug monograph relevance; no specific FDA restrictions under MoCRA or 21 CFR
Assessment
Ratings
Reference