Emollients

Ambrettolide

INCI: AMBRETTOLIDE
CAS 7779-50-2 EC 231-929-1
1-Oxacycloheptadec-7-en-2-one; 6-Hexadecen-16-olide
Limited Data
Insufficient safety data available. Consider enriching this ingredient.
Details

Description

1-Oxacycloheptadec-7-en-2-one; 6-Hexadecen-16-olide

Purpose

Function

Fragrance, Masking
Profile

Properties

Silicone
Silicone free
Compliance

Regulatory Status

EU
Permitted
Safety
GOOD
US
Permitted
Absorptionlow
Sensitizationlow
MoSadequate
NOAEL333 mg/kg
ConcernLow
Flags
fragrancemuskmacrocyclicbiodegradableifra_fragrancefda_food_additive
Verdict

Ambrettolide is a macrocyclic musk lactone with a clean safety profile: unrestricted by IFRA, non-sensitizing, biodegradable, and not flagged as an endocrine disruptor at cosmetic use levels.

US Note

Used as fragrance ingredient; IFRA 51st Amendment imposes no quantitative restrictions

Assessment

Ratings

Comedogenic0/5
LowHigh
Irritancy0/5
LowHigh
Reference

Identifiers

CAS Number
7779-50-2
EC Number
231-929-1
INCI
AMBRETTOLIDE
Category
Emollients
Updated
Apr 2, 2026