Allatoin. Microcrystalline Wax

Microcrystalline Wax (CAS 64742-60-5; EU INCI: Cera Microcristallina) is permitted without concentration limits under EU Cosmetics Regulation 1223/2009 and holds GRAS status in the US (21 CFR 172.886). Dermal absorption is negligible due to high molecular weight, eliminating systemic exposure concerns. CIR (1984/2005), EFSA (2023), German BfR (2018), and JECFA (1995) all confirm safety with no genotoxicity, carcinogenicity, or sensitization concern; pharmaceutical-grade purity and compliance with Cosmetics Europe Recommendation No. 14 for lip products is required.

GRAS status confirmed. Listed in FDA Inactive Ingredients Database for topical, oral, and vaginal preparations. Permitted under 21 CFR 172.886 (food contact) and 21 CFR 178.3710. No sunscreen active classification. No specific cosmetic use restrictions; CIR safety assessment (1984, reaffirmed 2005) supports safe use.