Skin Conditioning

Allantoin Calcium Pantothenate

INCI: ALLANTOIN CALCIUM PANTOTHENATE
CAS 4207-41-4
.beta.-Alanine, N-(2,4-dihydroxy-3,3-dimethyl-1-oxobutyl)-, calcium salt (2:1), (R)-, compound with 2,5-dioxo-4-imidazolydinyl urea
Limited Data
Insufficient safety data available. Consider enriching this ingredient.
Details

Description

.beta.-Alanine, N-(2,4-dihydroxy-3,3-dimethyl-1-oxobutyl)-, calcium salt (2:1), (R)-, compound with 2,5-dioxo-4-imidazolydinyl urea

Purpose

Function

Skin Conditioning, Skin Protecting, Soothing
Profile

Properties

Silicone
Silicone free
Compliance

Regulatory Status

EU
Permitted
Safety
MODERATE
US
Permitted
Absorptionlow
Sensitizationnone
MoSnot established
ConcernModerate
Verdict

Minor data gap: CIR assessed allantoin panthenol, not this specific calcium salt form. Difference is the pantothenate counter-ion (calcium salt vs. alcohol). Safety can reasonably be inferred but not directly claimed from CIR. If building a safety dossier, document this distinction.

US Note

Not restricted. CIR reviewed allantoin panthenol (pantothenyl alcohol), not calcium pantothenate specifically. However, panthenol was found safe (≤5%), and calcium pantothenate (provitamin B5 salt) is GRAS as a nutrient.

Assessment

Ratings

Comedogenic0/5
LowHigh
Irritancy0/5
LowHigh
Reference

Identifiers

CAS Number
4207-41-4
INCI
ALLANTOIN CALCIUM PANTOTHENATE
Category
Skin Conditioning
Updated
Apr 2, 2026