Adenosine(Anti-Wrinkle Agent)
Also known as Adenosin
INCI: ADENOSINE
CAS 58-61-7
Skin-conditioning agent, anti-aging, purine nucleoside, collagen stimulator, anti-wrinkle agent, adenosine receptor agonist in fibroblasts
Limited Data
Insufficient safety data available. Consider enriching this ingredient.
Details
Description
Skin-conditioning agent, anti-aging, purine nucleoside, collagen stimulator, anti-wrinkle agent, adenosine receptor agonist in fibroblasts
Purpose
Function
Skin-conditioning agent, anti-aging, purine nucleoside, collagen stimulator, anti-wrinkle agent, adenosine receptor agonist in fibroblasts
Profile
Properties
Silicone
Silicone free
Compliance
Regulatory Status
EU
Permitted
Safety
EXCELLENT
US
Permitted
Absorptionlow
Sensitizationnone
MoSnot established
ConcernNone
Flags
cir-safe-as-used-2023japan-quasi-drug-wrinklekorea-functional-cosmetic-0.04pctnon-genotoxicnon-sensitizing-hript-n205no-annex-listinganti-wrinkle-claims-jurisdiction-dependentkorea-method2-dec2025cosmos-fermentation
Verdict
CIR safe as used (2023). Japan quasi-drug wrinkle improvement. Korea MFDS functional cosmetic with wrinkle care at ≥0.04%. Non-genotoxic (Ames negative). Non-sensitizing (HRIPT n=205). No Annex listings. Anti-wrinkle claims cross drug boundary in EU/US/China. COSMOS eligible via fermentation.
US Note
No specific FDA restrictions. Anti-wrinkle claims must remain cosmetic-safe. Adenosine is also an Rx drug (Adenocard IV) but irrelevant to cosmetic use.
Assessment
Ratings
Reference