Adapalene Usp
skin-conditioning, anti-aging
Limited Data
Insufficient safety data available. Consider enriching this ingredient.
Details
Description
skin-conditioning, anti-aging
Purpose
Function
skin-conditioning, anti-aging
Profile
Properties
Silicone
Silicone free
Compliance
Regulatory Status
EU
Restricted
Safety
GOOD
US
Permitted
EU Max Concentration0.1%
Absorptionmoderate
Sensitizationlow
MoSadequate
NOAEL1.2 mg/kg
ConcernLow
Verdict
Third-generation synthetic retinoid selective for RAR-beta/gamma. Less irritating than tretinoin with added anti-inflammatory properties. 0.1% available OTC in the US for acne; strong anti-aging evidence at 0.3%. Preferred option for sensitive skin among retinoids.
US Note
0.1% OTC approved for acne; 0.3% Rx. Anti-inflammatory retinoid with selective RAR binding.
Assessment
Ratings
Reference
Identifiers
No registry identifiers available for this ingredient.