Acetyl Tetrapeptide-5
INCI: ACETYL TETRAPEPTIDE-5
CAS Insufficient Data
Acetyl Tetrapeptide-5 is product obtained by the acetylation of Tetrapeptide-5
Limited Data
Insufficient safety data available. Consider enriching this ingredient.
Details
Description
Acetyl Tetrapeptide-5 is product obtained by the acetylation of Tetrapeptide-5
Purpose
Function
Anti-edema peptide for periorbital area. Mechanism: ACE inhibition — dose-dependent inhibition of angiotensin-converting enzyme reduces microvascular pressure; reduced vascular permeability — decreases endothelial cell permeability, inhibiting interstitial fluid leakage; anti-glycation — protects collagen and SOD from fructose-mediated glycation, preserving elasticity. Strengthens capillary walls, reduces dark circle appearance.
Profile
Properties
Silicone
Silicone free
Compliance
Regulatory Status
EU
Permitted
Safety
EXCELLENT
US
Permitted
Absorptionnegligible
Sensitizationnone
MoSnot established
ConcernNone
Verdict
Acetyl Tetrapeptide-5 has triple-mechanism clinical substantiation for periorbital puffiness and dark circles: ACE inhibition, reduced vascular permeability, and anti-glycation, with in-vivo studies confirming in-vitro findings and no safety concerns.
US Note
No specific FDA restrictions. No pre-market approval required under MoCRA.
Assessment
Ratings
Reference