Active Compound

Acetyl Tetrapeptide-33

Signal peptide; ECM protein synthesis stimulant; follicle anchoring; hair-growth active
Limited Data
Insufficient safety data available. Consider enriching this ingredient.
Details

Description

Signal peptide; ECM protein synthesis stimulant; follicle anchoring; hair-growth active

Purpose

Function

Signal peptide; ECM protein synthesis stimulant; follicle anchoring; hair-growth active
Profile

Properties

Silicone
Silicone free
Compliance

Regulatory Status

EU
Permitted
Safety
GOOD
US
Permitted
Absorptionnegligible
Sensitizationnone
MoSadequate
ConcernLow
Verdict

Acetyl Tetrapeptide-3 is the peptide component of the Capixyl complex that stimulates synthesis of ECM proteins anchoring the hair follicle, reducing perifollicular inflammation and strengthening follicle structure. Clinical studies demonstrate significant efficacy against androgenetic alopecia with no adverse effects at 5% use level.

US Note

Permitted cosmetic active. Key component of Capixyl proprietary complex at suggested 5% use level.

Assessment

Ratings

Comedogenic0/5
LowHigh
Irritancy0/5
LowHigh
Reference

Identifiers

Category
Active Compound
Updated
Apr 23, 2026

No registry identifiers available for this ingredient.