Skin Conditioning

Acetyl Hexapeptide-9

Skin conditioning — anti-aging; stimulates collagen I, III, IV synthesis; boosts laminin-5, integrins; strengthens dermal-epidermal junction (DEJ)
Limited Data
Insufficient safety data available. Consider enriching this ingredient.
Details

Description

Skin conditioning — anti-aging; stimulates collagen I, III, IV synthesis; boosts laminin-5, integrins; strengthens dermal-epidermal junction (DEJ)

Purpose

Function

Skin conditioning — anti-aging; stimulates collagen I, III, IV synthesis; boosts laminin-5, integrins; strengthens dermal-epidermal junction (DEJ)
Profile

Properties

Silicone
Silicone free
Compliance

Regulatory Status

EU
Permitted
Safety
MODERATE
US
Permitted
Absorptionlow
Sensitizationlow
MoSadequate
ConcernModerate
Verdict

No CIR or SCCS opinion. Commercially available from multiple suppliers (Collaxyl™ IS) but safety assessment relies on peptide class read-across. A CPSR Safety Assessor may require supplier tox data or formal read-across justification.

US Note

Permitted — not restricted under 21 CFR; no dedicated CIR review published

Assessment

Ratings

Comedogenic0/5
LowHigh
Irritancy0/5
LowHigh
Reference

Identifiers

Category
Skin Conditioning
Updated
Apr 23, 2026

No registry identifiers available for this ingredient.