Skin Conditioning

Acetyl Hexapeptide-39

INCI: ACETYL HEXAPEPTIDE-39
CAS Not publicly listed
Acetyl Hexapeptide-39 is the product obtained by the acetylation of Hexapeptide-39
Limited Data
Insufficient safety data available. Consider enriching this ingredient.
Details

Description

Acetyl Hexapeptide-39 is the product obtained by the acetylation of Hexapeptide-39

Purpose

Function

Skin conditioning, anti-cellulite/body contouring agent that inhibits PGC-1α expression, slowing adipocyte differentiation
Profile

Properties

Silicone
Silicone free
Compliance

Regulatory Status

EU
Permitted
Safety
GOOD
US
Permitted
Absorptionlow
Sensitizationnone
MoSnot established
ConcernLow
Verdict

Mechanism involves adipogenesis modulation; topical exposure at cosmetic levels is not expected to produce systemic effects.

US Note

Permitted

Assessment

Ratings

Comedogenic0/5
LowHigh
Irritancy0/5
LowHigh
Reference

Identifiers

CAS Number
Not publicly listed
INCI
ACETYL HEXAPEPTIDE-39
Category
Skin Conditioning
Updated
Apr 2, 2026