Skin Conditioning

Acetyl Hexapeptide-37

INCI: ACETYL HEXAPEPTIDE-37
CAS 1447824-16-9
Acetyl Hexapeptide-37 is the product obtained by the acetylation of Hexapeptide-37
Limited Data
Insufficient safety data available. Consider enriching this ingredient.
Details

Description

Acetyl Hexapeptide-37 is the product obtained by the acetylation of Hexapeptide-37

Purpose

Function

Skin Conditioning, Hydrating (Aquaporin-3 booster — enhances water transport from basal epidermis to stratum corneum)
Profile

Properties

Silicone
Silicone free
Compliance

Regulatory Status

EU
Permitted
Safety
GOOD
US
Permitted
Absorptionlow
Sensitizationnone
MoSnot established
ConcernLow
Verdict

Well-documented mechanism of AQP3 upregulation with barrier function improvement and collagen I synthesis stimulation; no adverse signals reported.

US Note

Permitted

Assessment

Ratings

Comedogenic0/5
LowHigh
Irritancy0/5
LowHigh
Reference

Identifiers

CAS Number
1447824-16-9
INCI
ACETYL HEXAPEPTIDE-37
Category
Skin Conditioning
Updated
Apr 2, 2026