conditioning-agent

Acetyl Glutamine

INCI: ACETYL GLUTAMINE
CAS 35305-74-9 EC 219-647-7
L-Glutamine, N-acetyl-
Limited Data
Insufficient safety data available. Consider enriching this ingredient.
Details

Description

L-Glutamine, N-acetyl-

Purpose

Function

Skin conditioning agent; moisture barrier support
Profile

Properties

Silicone
Silicone free
Compliance

Regulatory Status

EU
Permitted
Safety
GOOD
US
Permitted
Absorptionlow
Sensitizationnone
MoSnot established
ConcernLow
Flags
skin-conditioningamino-acid-derivativehumectantbarrier-supportcir-reviewed
Verdict

Acetyl Glutamine (CAS 35305-74-9) is permitted in the EU with no restrictions under Regulation EC 1223/2009 and freely permitted in the US with no FDA concentration limits; CIR 2013 alpha-amino acids assessment concluded safety for cosmetic use.

US Note

No FDA restriction; CIR 2013 alpha-amino acids assessment concluded safe for cosmetic use

Assessment

Ratings

Comedogenic0/5
LowHigh
Irritancy0/5
LowHigh
Reference

Identifiers

CAS Number
35305-74-9
EC Number
219-647-7
INCI
ACETYL GLUTAMINE
Category
conditioning-agent
Updated
Apr 2, 2026