Solvent

Acetone

INCI: ACETONE
CAS 67-64-1 EC 200-662-2
Acetone
Limited Data
Insufficient safety data available. Consider enriching this ingredient.
Details

Description

Acetone

Purpose

Function

Solvent, denaturant
Profile

Properties

Silicone
Silicone free
Compliance

Regulatory Status

EU
Permitted
Safety
MODERATE
US
Permitted
Absorptionhigh
Sensitizationlow
MoSadequate
NOAEL200 mg/kg
ConcernModerate
Flags
endocrine_disruptorepa_safer_alternativeifra_fragrancefda_food_additivejecfa_safe
Verdict

Potent defatting agent causing dryness, cracking, and irritant contact dermatitis with repeated dermal exposure. Inhalation risk as CNS depressant at high concentrations. VOC with workplace exposure limits (OSHA PEL 1000 ppm TWA). Flammable; adequate ventilation required in nail salon applications.

US Note

Permitted without specific restriction. FDA GRAS for food contact. Widely used in OTC drug products (nail polish removers).

Assessment

Ratings

Comedogenic0/5
LowHigh
Irritancy0/5
LowHigh
Reference

Identifiers

CAS Number
67-64-1
EC Number
200-662-2
INCI
ACETONE
Category
Solvent
Updated
Apr 2, 2026