Antioxidant

A-Tocopherol

Antioxidant; chain-breaking free radical scavenger (HAT mechanism); lipophilic skin-conditioning agent; product stabiliser against oxidative rancidity; photoprotective booster
Limited Data
Insufficient safety data available. Consider enriching this ingredient.
Details

Description

Antioxidant; chain-breaking free radical scavenger (HAT mechanism); lipophilic skin-conditioning agent; product stabiliser against oxidative rancidity; photoprotective booster

Purpose

Function

Antioxidant; chain-breaking free radical scavenger (HAT mechanism); lipophilic skin-conditioning agent; product stabiliser against oxidative rancidity; photoprotective booster
Profile

Properties

Silicone
Silicone free
Compliance

Regulatory Status

EU
Permitted
Safety
EXCELLENT
US
Permitted
Absorptionhigh
Sensitizationlow
MoSadequate
NOAEL130 mg/kg
ConcernNone
Verdict

Gold-standard lipophilic antioxidant for both product stabilisation and skin anti-aging benefit. Effective at 0.01–0.05% as product antioxidant; 0.05–1% for skin benefit. Photosensitive in pure form — opaque/airless packaging is mandatory. The C+E+ferulic acid combination clinically inhibits UV-induced erythema, sunburn cell formation, and thymine dimer DNA damage. Vitamin C regenerates oxidised vitamin E — making C+E synergistic rather than additive. Ferulic acid at 0.5% doubles the photoprotective capacity of this combination. No regulatory restrictions.

US Note

FDA GRAS for food use (21 CFR 182.3890). CIR Expert Panel final report confirms safety of tocopherol, tocopheryl acetate, and mixed tocopherols as used in cosmetics at typical use levels (0.01–1%). No concentration limits for cosmetic use.

Assessment

Ratings

Comedogenic0/5
LowHigh
Irritancy0/5
LowHigh
Reference

Identifiers

Category
Antioxidant
Updated
Apr 23, 2026

No registry identifiers available for this ingredient.