A-Hexil Cinnamaldehyde

Cinnamon bark oil containing cinnamaldehyde activates TRPA1 receptors for plumping via irritant vasodilation, but is one of the most significant fragrance contact allergens with IFRA restrictions and EU declaration requirements at >0.001% in leave-on products. Mucosal application at the lip vermilion amplifies sensitization risk, and repeated use can induce chronic contact cheilitis; use at lowest effective concentration and avoid in sensitive skin.

Permitted at low concentrations for cosmetic use; cinnamaldehyde classified as fragrance allergen; IFRA guidelines should be followed; plumping claims via TRPA1 receptor activation may border on drug action claims; oral ingestion from lip products adds to cinnamaldehyde systemic exposure