4-Trihydroxybenzene
Hair colorant (auto-oxidative dye)
Limited Data
Insufficient safety data available. Consider enriching this ingredient.
Details
Description
Hair colorant (auto-oxidative dye)
Purpose
Function
Hair colorant (auto-oxidative dye)
Profile
Properties
Silicone
Silicone free
Compliance
Regulatory Status
EU
Banned
Safety
POOR
US
Permitted
Absorptionnegligible
Sensitizationmoderate
MoSadequate
NOAEL5.56 mg/kg
ConcernHigh
Verdict
Genotoxic in vitro (mutagenic in Ames tests, DNA strand breaks, SCE); generates ROS and hydrogen peroxide via auto-oxidation; benzene metabolite; SCCS concluded unsafe due to genotoxicity
US Note
Permitted as coal tar hair dye with mandatory caution statement and patch test instructions per FD&C Act; CIR Panel concluded safe as hair dye at current use (up to 2.5%)
Assessment
Ratings
Reference
Identifiers
No registry identifiers available for this ingredient.