Preservative

4-Hydroxyacetophenone

Preservative Booster, Antimicrobial, Skin Conditioning, Antioxidant
Limited Data
Insufficient safety data available. Consider enriching this ingredient.
Details

Description

Preservative Booster, Antimicrobial, Skin Conditioning, Antioxidant

Purpose

Function

Preservative Booster, Antimicrobial, Skin Conditioning, Antioxidant
Profile

Properties

Silicone
Silicone free
Compliance

Regulatory Status

EU
Permitted
Safety
GOOD
US
Permitted
Absorptionmoderate
Sensitizationlow
MoSnot established
NOAEL45 mg/kg
ConcernLow
Verdict

Hydroxyacetophenone is a key component of scientifically validated preservative combinations that selectively inhibit pathogenic bacteria while preserving beneficial skin commensals, making it a strong candidate for microbiome-certified and sensitive skin formulations.

US Note

Permitted in OTC cosmetics; no specific FDA concentration limits; used as multifunctional preservative booster in hurdle technology systems; MoCRA 2026 compliance required

Assessment

Ratings

Comedogenic0/5
LowHigh
Irritancy0/5
LowHigh
Reference

Identifiers

Category
Preservative
Updated
Apr 23, 2026

No registry identifiers available for this ingredient.