Colorant

4-Amino-2-Hydroxytoluene

INCI: 4-AMINO-2-HYDROXYTOLUENE
CAS 2835-99-6 EC 220-618-6
5-amino-o-cresol
Limited Data
Insufficient safety data available. Consider enriching this ingredient.
Details

Description

5-amino-o-cresol

Purpose

Function

Hair dyeing (oxidative hair dye coupler)
Profile

Properties

Silicone
Silicone free
Compliance

Regulatory Status

EU
Banned
Safety
POOR
US
Permitted
Absorptionmoderate
Sensitizationmoderate
MoSadequate
NOAEL50 mg/kg
ConcernModerate
Flags
eu_cosing_listed
Verdict

Must not be used with nitrosating agents. Mandatory consumer warning: Hair colorants can cause severe allergic reactions. Not intended for persons under 16. Patch test recommended before each use.

US Note

Permitted under coal tar hair dye exemption (21 USC §361(a)); CIR concluded safe for use as a hair dye ingredient at current practices of use and concentration

Assessment

Ratings

Comedogenic0/5
LowHigh
Irritancy0/5
LowHigh
Reference

Identifiers

CAS Number
2835-99-6
EC Number
220-618-6
INCI
4-AMINO-2-HYDROXYTOLUENE
Category
Colorant
Updated
Apr 2, 2026