Fragrance

2-Methylbutyric Acid

INCI: 2-METHYLBUTYRIC ACID
CAS 116-53-0 EC 204-145-2
2-Methylbutyric acid
Limited Data
Insufficient safety data available. Consider enriching this ingredient.
Details

Description

2-Methylbutyric acid

Purpose

Function

Fragrance ingredient
Profile

Properties

Silicone
Silicone free
Compliance

Regulatory Status

EU
Permitted
Safety
GOOD
US
Permitted
Absorptionmoderate
Sensitizationlow
MoSadequate
NOAEL50 mg/kg
ConcernLow
Flags
fragrance-componentifra_fragrancefda_food_additivejecfa_safe
Verdict

Corrosive/irritant at high concentrations (pH-dependent); must be used at appropriate dilution; strong odor

US Note

Permitted — FEMA GRAS; no FDA restriction

Assessment

Ratings

Comedogenic0/5
LowHigh
Irritancy0/5
LowHigh
Reference

Identifiers

CAS Number
116-53-0
EC Number
204-145-2
INCI
2-METHYLBUTYRIC ACID
Category
Fragrance
Updated
Apr 2, 2026