2 Propanediol
Humectant; solvent; antimicrobial contributor; water activity reduction agent; self-preservation contributor
Limited Data
Insufficient safety data available. Consider enriching this ingredient.
Details
Description
Humectant; solvent; antimicrobial contributor; water activity reduction agent; self-preservation contributor
Purpose
Function
Humectant; solvent; antimicrobial contributor; water activity reduction agent; self-preservation contributor
Profile
Properties
Silicone
Silicone free
Compliance
Regulatory Status
EU
Permitted
Safety
EXCELLENT
US
Permitted
Absorptionnegligible
Sensitizationnone
MoSadequate
NOAEL1000 mg/kg
ConcernNone
Verdict
Propanediol (CAS 504-63-2) is permitted without restriction under EU Cosmetics Regulation 1223/2009 and holds FDA GRAS status (GRN No. 302, 2009), with a wide margin of safety for cosmetic use up to 39.9%, minimal dermal absorption (0.12% at 48h), and a clean sensitization profile.
US Note
FDA GRAS status confirmed via GRN No. 302 (September 7, 2009) for food use; no cosmetic-specific restrictions under FD&C Act. Not an OTC monograph ingredient. Fully permitted for cosmetic use without limitation.
Assessment
Ratings
Reference
Identifiers
No registry identifiers available for this ingredient.